Foto: Stefan Zimmerman
Aging Research Center (ARC) E-mail:miia.kivipelto@ki.se |
Miia Kivipelto is professor of Clinical Geriatric Epidemiology at Karolinska Institutet and a senior geriatrician at the Karolinska University Hospital She is also deputy head of the Aging Research Center.
Miia’s research focuses on prevention, early diagnosis and treatment of cognitive impairment, dementia and Alzheimer’s disease (AD). Through epidemiological studies she has identified midlife vascular and lifestyle risk factors for later dementia/AD and aims to build on these observations to improve knowledge transfer and public awareness and to design intervention trials to mitigate these factors including lifestyle manipulations, such as exercise interventions.
Miia is principal investigator for the population-based study Cardiovascular Risk Factors, Aging and Dementia (CAIDE) and the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)one of the first multi-domain intervention studies in the world aimed at preventing or postponing dementia. She is also part of a Europe’s first-ever European Dementia Prevention Initiative (EDPI). In addition she is involved in two population-based studies in Stockholm (Kungsholmen Project and SNACK) and is responsible for the clinical database (Gedoc) at the Memory Clinic, Karolinska University Hospital.
Miia leads a group of multidisciplinary researchers that includes 4 postdocs and 9 doctoral students. Her group has close connections with the University of Eastern Finland and the National Institute of Health and Welfare in Helsinki and this collaboration has led to the development of the Nordic Brain Network (NBN), which has increased the utilization and exchange of resources and information about aging. She is also involved in many international networks and scientific/steering committees.
As of September 2011 Miia’s scientific production has led to 120 articles in peer reviewed journals, seven book chapters and approximately 200 congress abstracts. The average number of citations per item is 25.14, h-index 23.
Miia has received several awards including: Junior Chamber International: Ten Outstanding Young Persons of the World 2011; Academy of Finland Award for Social Impact 2009; The Association of European Psychiatrists and European Bristol-Myers Squibb Prevention Award in Psychiatry 2007 and Martti Hämäläinen’s Award for Young Researcher 2002.
Selected publications
10 selected publications from the AivoCog group out of 120 articles published/accepted or submitted for publication in peer-reviewed journals
The articles have received many citations (average citation per item 25.14, h-index 23), and citations have increased exponentially from 2002-2009 (2004: approx 100 citations, 2006: 300, 2009: 600). Sum of the times cited: 2 941 (average citation per year 196). The most cited original article: Kivipelto et al., “Midlife vascular risk factors and Alzheimer’s disease in later life: longitudinal, population based study”. BMJ 2001;322:1447-1451 with 439 citations.
1. Kivipelto M, Helkala E-L, Laakso MP, Hänninen T, Hallikainen M, Alhainen K, Soininen H, Tuomilehto J, Nissinen A. Midlife vascular risk factors and Alzheimer’s disease in later life: longitudinal, population based study. BMJ 2001;322:1447-1451.
2. Anttila T, Helkala E-L, Viitanen M, Kåreholt I, Fratiglioni L, Winblad W, Soininen H, Tuomilehto J, Nissinen A, Kivipelto M. Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population-based study. BMJ 2004;329:539-542.
3. Rovio S, Kåreholt I, Helkala E-L, Viitanen M, Winblad B, Tuomilehto J, Soininen H, Nissinen A, Kivipelto M. Leisure time physical activity at midlife and the risk of dementia and Alzheimer’s disease. Lancet Neurology 2005;4:705-11.
4. Kivipelto M, Ngandu T, Laatikainen T, Winblad B, Soininen H, Tuomilehto J. Risk Score for prediction of dementia risk in 20 years among middle aged people: a longitudinal population based study. Lancet Neurology 2006;9:735-41.
5. Solomon A, Kåreholt I, Ngandu T, Winbald B, Nissinen A, Tuomilehto J, Soininen H, Kivipelto M. Serum cholesterol changes after midlife and late-life cognition: 21-year follow-up study. Neurology 2007; 68:751-6
6. Kivipelto M, Rovio S, Ngandu T, Kåreholt I, Laitinen M, Winblad B, Hachinski V, Cedazo-Minguez A, Soininen H, Tuomilehto J, NissinenA. Apolipoprotein E ε4 Magnifies Lifestyle Risks for Dementia: A Population Based Study. Journal of Cellular and Molecular Medicine 2008 12(6B):2762-71.
7. Håkanson K, Rovio S, Helkala E-L, Winblad B, Vilska A-R, Soininen H, Nissinen A, Mohammed A, Kivipelto M. Association between mid-life marital status and cognitive function in later life: population based cohort study. BMJ 2009; Jul2;339:b2462. doi: 10.1136/bmj.b2462.
8. Ahtiluoto S, Polvikoski T, Peltola M, Solomon A, Winblad B, Sulkava R, Kivipelto M. Diabetes, Alzheimer's Disease, and Vascular Dementia: a population-based neuropathological study. Neurology 2010 Sep 28;75(13):1195-202. Epub 2010 Aug 25.
9. Hooshmand B, Solomon A, Kåreholt I, Rusanen M, Leiviskä J, Soininen H, Kivipelto M. Homocysteine and holotranscobalamin and the risk of Alzheimer's disease. Neurology 2010 Oct 19;75(16):1408-14.
10. Mangialasche F, Solomon A, Mecocci P, Winblad B, Kivipelto M. Alzheimer’s disease: clinical trials and drug development. Lancet Neurology 2010; 9: 702-16.